Thermo Fisher Scientific Nogo Receptor Recombinant Rabbit Monoclonal Antibody (ARC0872)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0872

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-400 of human NOGO Receptor 1 (RTN4R) (Q9BZR6) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Nogo Receptor,uniProtId:Q9BZR6-1,ncbiNodeId:9606,antigenRange:300-400,antigenLength:473,antigenImageFileName:MA5-35423_Nogo_Receptor_Q9BZR6-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35423_Nogo_Receptor_Q9BZR6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849324

Product Specific Information

Immunogen sequence: RLAANDLQGC AVATGPYHPI WTGRATDEEP LGLPKCCQPD AADKASVLEP GRPASAGNAL KGRVPPGDSP PGNGSGPRHI NDSPFGTLPG SAEPPLTAVR P

Target Information

NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.