Thermo Fisher Scientific Nogo Receptor Recombinant Rabbit Monoclonal Antibody (ARC0872)
Nogo Receptor를 인식하는 재조합 토끼 단클론 항체로 Western blot 및 ELISA에 적합. 인간과 생쥐 시료에 반응. HEK293 발현 시스템에서 생산된 IgG 형 항체로, 액상 형태이며 -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0872 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 300–400 of human NOGO Receptor 1 (RTN4R) (Q9BZR6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.42 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849324 |
Product Specific Information
Immunogen sequence:
RLAANDLQGC AVATGPYHPI WTGRATDEEP LGLPKCCQPD AADKASVLEP GRPASAGNAL KGRVPPGDSP PGNGSGPRHI NDSPFGTLPG SAEPPLTAVR P
Target Information
NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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