Thermo Fisher Scientific NAIF1 Polyclonal Antibody
Rabbit polyclonal antibody against human NAIF1 protein. Validated for ICC/IF applications. Supplied as a liquid, unconjugated form with 0.2 mg/mL concentration. Recommended for research use only, not for diagnostic or resale purposes.
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Applications and Tested Dilution
- Application: Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NAIF1. Recombinant protein control fragment (Product #RP-106581) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663646 |
Product Specific Information
Immunogen sequence:
TVTLTQIPTET TYHTLEEGVV EYCTAEAPPP LPPETPVDMM AQHADTSVKP QALKSRIALN SAKLIQEQRV TNLHVKEIAQ HL
- Highest antigen sequence identity to orthologs: mouse 92%, rat 90%.
Target Information
Human NAIF1 is located on chromosome 9q34.11 and encodes a 327-amino-acid protein with a homeodomain-like region and two nuclear localization signals at its N-terminal region.
NAIF1 is conserved across species including human, mouse, crab-eating macaque, dog, chicken, and frog, and shows no clear homology to known genes or proteins.
It is predominantly localized in the nucleus. Overexpression of NAIF1 inhibits cell growth and induces apoptosis, accompanied by decreased mitochondrial membrane potential and caspase-3 activation.
In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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