Thermo Fisher Scientific SPANX-C Polyclonal Antibody
인간 SPANX-C 단백질에 특이적인 토끼 다클론 항체로, WB, IHC, ELISA에 적합합니다. Protein A로 정제된 고순도 항체이며, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다. 암세포 표지 및 생식세포 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (IHC) | 1.25–2.5 µg/mL |
| ELISA | 1:5,000–1:20,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | This Protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full-length recombinant human SPANX-C protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 5 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at 4°C prior to restoration.
- For extended storage, aliquot contents and freeze at -20°C or below.
- Avoid freeze/thaw cycles.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
This Protein A purified antibody is directed against human SPANX-C protein.
A protein-protein BLAST analysis suggests cross-reactivity with most SPANX proteins from human, gorilla, and chimpanzee.
Reactivity against other homologues is not known.
Target Information
Temporally regulated transcription and translation of several testis-specific genes are required for the formation of mature spermatozoa.
This gene is part of the SPANX family located on chromosome X and encodes testis-specific proteins that localize to various subcellular compartments.
The SPANX-C protein localizes to the nucleus and is expressed in highly metastatic cell lines, making it a potential diagnostic and prognostic marker.
As a member of the cancer/testis antigen family, it represents a potential target for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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