Thermo Fisher Scientific TLR9 Polyclonal Antibody
TLR9 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ELISA 등에 사용 가능하며, 면역원은 human TLR9의 414-543 아미노산 서열 기반입니다. 액상 형태로 -20°C 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 414–543 of human TLR9 (NP_059138.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.53 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805867 |
Product Specific Information
- Positive Samples: Mouse spleen, Rat spleen
- Cellular Location: Cytoplasmic vesicle, Endoplasmic reticulum membrane, Endosome, Lysosome, Single-pass type I membrane protein, Phagosome
Immunogen sequence:
FPGLRYVDLS DNRISGASEL TATMGEADGG EKVWLQPGDL APAPVDTPSS EDFRPNCSTL NFTLDLSRNN LVTVQPEMFA QLSHLQCLRL SHNCISQAVN GSQFLPLTGL QVLDLSHNKL DLYHEHSFTE
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.
They recognize pathogen-associated molecular patterns on infectious agents and mediate cytokine production necessary for effective immunity.
TLR9 is preferentially expressed in immune cell-rich tissues such as spleen, lymph node, bone marrow, and peripheral blood leukocytes. It mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to trigger innate immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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