
Thermo Fisher Scientific CD1a/HTA1 (Mature Langerhans Cells Marker) Monoclonal Antibody (C1A/3249)
인간 CD1a 단백질을 인식하는 마우스 단클론 항체로, 성숙 랑게르한스 세포 표지자로 사용됨. ELISA 및 Peptide Array에 적용 가능하며, 비결합형 액상 형태로 제공됨. 단백질 A/G 정제, PBS(pH 7.4) 저장, 연구용으로만 사용.
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Applications
ELISA
- Assay-dependent
Peptide Array
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1A/3249 |
| Immunogen | Recombinant fragment (around aa43–173) of human CD1A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD1a is a non-polymorphic MHC Class I–related cell surface glycoprotein expressed in association with beta-2 microglobulin. It is found on cortical thymocytes, epidermal Langerhans cells, dendritic cells, certain T-cell leukemias, and other tissues. CD1a mediates presentation of lipid and glycolipid antigens to T cells. The human genome contains five CD1 family genes (CD1a, b, c, d, e) organized on chromosome 1. CD1a localizes to the plasma membrane and early endocytic vesicles. Alternatively spliced transcript variants of CD1a have been observed, though their biological validity is undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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