Thermo Fisher Scientific SOX2 Recombinant Rabbit Monoclonal Antibody (2E1)
SOX2 단백질을 인식하는 토끼 단클론 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot, IHC, ICC/IF에 적합하며, 줄기세포 유지 및 발달 관련 연구에 유용합니다. 고순도 정제 및 안정한 액상 포맷으로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2E1 |
| Immunogen | A synthesized peptide derived from human SOX2 (amino acids 6–19) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898332 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and determination of cell fate. The SOX2 protein is essential for stem-cell maintenance in the central nervous system and regulates gene expression in the stomach. The SOX2 gene is located within an intron of another gene, SOX2 overlapping transcript (SOX2OT). SOX2 may act as a transcriptional activator by forming complexes with other proteins. Mutations in SOX2 are associated with bilateral anophthalmia, optic nerve hypoplasia, and syndromic microphthalmia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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