Thermo Fisher Scientific GFAP Monoclonal Antibody (N206B/9), PerCP
GFAP 단백질을 인식하는 PerCP 결합 마우스 단클론 항체로, 사람, 생쥐, 랫트 시료에 반응합니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며 단백질 G로 정제되었습니다. 4°C에서 보관하며 보존제는 포함되어 있지 않습니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N206B/9 |
| Immunogen | Synthetic peptide amino acids 411–422 (KTVEMRDGEVIK) of human GFAP |
| Conjugate | PerCP |
| Excitation/Emission Max | 482/675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932090 |
Additional Formats Available:
Product Specific Information
- 100% identical in rat and mouse.
- 1 µg/mL of MA5-45636 was sufficient for detection of GFAP R416WT in 20 µg of rat brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 50 kDa.
- Does not cross-react with GFAP-R416W or other proteins (based on KO validation results).
- This antibody was formerly sold as clone S206B-9.
Target Information
GFAP (Glial fibrillary acidic protein) is a class III intermediate filament protein expressed in astrocytes and certain astroglia of the central nervous system, satellite cells of peripheral ganglia, and non-myelinating Schwann cells. It is also found in neural stem cells, lens epithelium, Kupffer cells, and some salivary tumor cells. GFAP serves as a marker to distinguish astrocytes from other glial cells during development. Mutations in GFAP cause Alexander disease, a rare astrocytic disorder. Multiple transcript variants exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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