Thermo Fisher Scientific Phospho-SOX9 (Ser181) Polyclonal Antibody
SOX9 단백질의 Ser181 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합. 액상 형태, 1 mg/mL 농도, -20°C 보관. 세포 분화 및 연골 형성 연구에 활용 가능.
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Thermo Fisher Scientific Phospho-SOX9 (Ser181) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human SOX9 around the phosphorylation site of Ser181 (R-K-SP-V-K) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554933 |
Target Information
SOX9 plays a critical role in sex determination and differentiation of Sertoli cells. It is involved in chondrogenesis and regulates the expression of genes associated with cartilage formation by acting as a transcription factor. Translocation of SOX9 can cause campomelic dysplasia. It contributes to testis formation from fetal gonads and supports the neuron-glia switch during spinal cord development. SOX9 also influences prostate epithelium growth and maintenance, and its dysregulation is linked to prostate cancer progression. Additionally, it is implicated in neural crest precursor formation and melanin production regulation. Expression is observed in adult testis, adult heart, and fetal brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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