Thermo Fisher Scientific RHEB Polyclonal Antibody
RHEB 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA에 사용 가능. Human 및 Mouse 반응성. Affinity Chromatography로 정제되었으며, -20°C에서 보관. 연구용으로 세포 성장 및 신호전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–180 of human RheB (NP_005605.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.45 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855705 |
Product Specific Information
Immunogen sequence:
MPQSKSRKIA ILGYRSVGKS SLTIQFVEGQ FVDSYDPTIE NTFTKLITVN GQEYHLQLVD TAGQDEYSIF PQTYSIDING YILVYSVTSI KSFEVIKVIH GKLLDMVGKV QIPIMLVGNK KDLHMERVIS YEEGKALAES WNAAFLESSA KENQTAVDVF RRIILEAEKM DGAASQGKSS
Target Information
Rheb encodes a member of the small GTPase superfamily and represents a lipid-anchored cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein plays a critical role in regulating growth and cell cycle progression through the insulin/TOR/S6K signaling pathway. It possesses GTPase activity, cycling between GDP- and GTP-bound forms, and requires farnesylation for its function. Three pseudogenes have been mapped — two on chromosome 10 and one on chromosome 22.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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