Thermo Fisher Scientific RPL14 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTQVRRQAM PFKCMQLTDF ILKFPHSAHQ KYVRQAWQKA DINTKWAATR WAKKIEARER KAKMTDFDRF KVMKAKKMRN RIIKNEVKKL QKAALLKASP KKAPGTKGTA AAAAAAAAAK VPAKKITAAS KKAPAQKVPA QKATGQKAAP APKAQKGQKA PAQKAPAPKA SGKKA

Positive Samples: HL-60, HeLa, 293T, Jurkat, HepG2, Mouse spleen, Mouse ovary, Rat spleen, Rat kidney

Target Information

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. These subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 60S subunit and belongs to the L14E family. It contains a basic region-leucine zipper (bZIP)-like domain and is located in the cytoplasm.
The gene includes a polymorphic trinucleotide (GCT) repeat tract, resulting in a stretch of alanine residues. Multiple transcript variants exist but encode the same protein. As typical for ribosomal protein genes, multiple processed pseudogenes are dispersed throughout the genome.

References:

• Aoki M., Diabetes 45:157–164 (1996)
• Tanaka M., Biochem. Biophys. Res. Commun. 243:531–537 (1998)
• Yoshihama M., Genome Res. 12:379–390 (2002)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.