Thermo Fisher Scientific Cbl-c Polyclonal Antibody
Human Cbl-c 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. 고순도 affinity chromatography 정제, 1.2 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:3,000 |
| ELISA | 1:10,000–1:50,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminal portion of Human Cbl-c |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate (pH 7.2), 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
This affinity-purified antibody is directed against human Cbl-c protein.
BLAST analysis suggests reactivity with Cbl-c from human and chimpanzee sources.
Partial reactivity expected with mouse and rat Cbl-c (~83% sequence homology).
No reactivity expected with Cbl-a or Cbl-b.
Target Information
Cbl-c is a member of the Cbl family of E3 ubiquitin ligases involved in tyrosine kinase downregulation via ubiquitination.
Expression may be restricted to epithelial cells.
Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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