Thermo Fisher Scientific FBXW11 Polyclonal Antibody
FBXW11 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FBXW11 (Accession Q9UKB1), corresponding to amino acid residues F503–R542. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850033 |
Product Specific Information
Antibody detects endogenous levels of total FBXW11.
Target Information
This gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid motif known as the F-box. F-box proteins are one of the four subunits of the ubiquitin protein ligase complex (SCFs: SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
F-box proteins are divided into three classes:
- Fbws: containing WD-40 domains
- Fbls: containing leucine-rich repeats
- Fbxs: containing other protein–protein interaction modules or no recognizable motifs
The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and alternative splicing generates three transcript variants differing by the presence or absence of two alternate exons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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