Thermo Fisher Scientific FMN2 Polyclonal Antibody
FMN2 단백질을 검출하기 위한 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 액상 형태로 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FMN2 (Accession Q9NZ56), corresponding to amino acid residues M1–T35 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850039 |
Product Specific Information
Antibody detects endogenous levels of total FMN2.
Target Information
FMN2 is a formin homology protein of the cappuccino subfamily, highly conserved among vertebrates. It shows similarity to formin-1, the founding member of the formin family, and plays a crucial role in maintaining the meiotic spindle. FMN2 is widely expressed in human fetal brain, adult brain, hypothalamus, retina, pancreatic islet, and germinal-center B cells. Its pathological role has been identified in various tumors such as parathyroid tumor, glioblastoma, retinoblastoma, and chondrosarcoma. Mutations in FMN2 are associated with unexplained infertility in women. The human FMN2 gene is localized at chromosomal region 1q43.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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