Thermo Fisher Scientific FBXW2 Polyclonal Antibody
FBXW2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot과 IHC(P)에서 사용 가능. Human, Mouse, Rat에 반응하며, 고순도의 Affinity chromatography로 정제됨. PBS, 50% glycerol 보존액에 저장되며 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FBXW2 (Accession Q9UKT8), corresponding to amino acid residues F382–T432 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850034 |
Product Specific Information
Antibody detects endogenous levels of total FBXW2.
Target Information
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins are critical for the ubiquitin-mediated degradation of cellular regulatory proteins. F-box proteins are one of the four subunits of ubiquitin protein ligases (SCFs), which bring ubiquitin conjugating enzymes to substrates specifically recruited by different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of WD-40 repeats, leucine-rich repeats, or other protein-protein interaction domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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