Thermo Fisher Scientific CD36 Polyclonal Antibody
CD36 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF 등 다양한 응용에 사용 가능. 인간 시료에 반응하며, 지방산 수송 및 대식세포 관련 연구에 적합. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100 | – |
| Miscellaneous (PubMed) | – | View 3 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the extracellular domain of human CD36 (Fatty acid translocase) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: CD36
Target Information
CD36, also known as scavenger receptor class B member 3, is a membrane protein expressed on macrophages, platelets, and adipocytes. It plays important roles in lipid metabolism, inflammation, and atherosclerosis, mediating recognition and uptake of ligands such as oxidized low-density lipoproteins, long-chain fatty acids, and apoptotic cells.
CD36 is also implicated in malaria pathogenesis and serves as a receptor for thrombospondin in platelets and various cell lines. It binds to collagen, thrombospondin, anionic phospholipids, and oxidized LDL, mediating cytoadherence of Plasmodium falciparum-infected erythrocytes.
Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been identified.
Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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