Thermo Fisher Scientific Bombesin Receptor 3 (extracellular) Polyclonal Antibody

Thermo Fisher Scientific Bombesin Receptor 3 (extracellular) Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Reconstitution: Add 50 µL or 0.2 mL double distilled water (DDW), depending on sample size.
• Ships as lyophilized powder at room temperature.
• Upon arrival, store at −20°C.
• Reconstituted solution: stable at 4°C for up to 1 week.
• For long-term storage, aliquot and keep at −20°C.
• Avoid repeated freeze/thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

BRS3 expression has been observed in lung (normal and cancer), nasal mucosa, placenta, and uterus. ESTs have been isolated from normal brain and kidney cancer libraries.

G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, sharing a structural motif of seven transmembrane helices. They exist in active and inactive forms, with ligand-induced conformational changes triggering G-protein signaling and downstream pathways.

Negative regulation of GPCRs plays a critical role in cellular physiology and pharmacological research. GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) demonstrate the therapeutic potential of this receptor family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지