Thermo Fisher Scientific CD26 (DPP IV/ADA-Binding Protein) Monoclonal Antibody (DPP4/910)
CD26(DPP IV/ADA-Binding Protein) 단클론 항체로 인간 및 랫트에 반응. IHC, ICC/IF, Flow Cytometry에 적합. 비결합형 액상 형태, 1 mg/mL 농도. Protein A/G 정제, -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific CD26 (DPP IV/ADA-Binding Protein) Monoclonal Antibody (DPP4/910)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DPP4/910 |
| Immunogen | Recombinant human DPP4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Does not react with Pig or Sheep.
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV, adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family.
It is expressed on lymphocytes and upregulated during T-cell activation, also found on activated B cells, natural killer cells, and epithelial tissues.
CD26 participates in diverse biological processes such as T-cell activation, cell adhesion to extracellular matrix components (fibronectin, collagens), and HIV infection.
It is identical to adenosine deaminase complexing protein-2 and T-cell activation antigen CD26.
This intrinsic membrane glycoprotein acts as a serine exopeptidase, cleaving X-proline dipeptides from polypeptide N-termini.
Altered CD26 activity is associated with malignant transformation, with enzymatic activity increasing with tumor grade and severity.
Expression changes have been reported in circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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