Thermo Fisher Scientific Human p53R2 Synthetic Peptide
인간 p53R2의 N-말단 16 아미노산 서열에 해당하는 합성 펩타이드로, PA5-19970 항체의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태이며 PBS(pH 7.2, 0.1% BSA) 버퍼에 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP0095
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to the 16 amino acid terminus of human p53R2.
PEP-0095 can be used as a blocking peptide with polyclonal antibody PA5-19970.
Target Information
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, have been discovered.
p53R2 is a p53-inducible gene containing a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. It is induced by reagents such as ultraviolet and gamma irradiation that cause DNA damage. The p53R2 gene product is directly involved in the p53 checkpoint for DNA repair. The isoform of the p53 family member p73 also induces p53R2 expression.
p53R2 is an important target of p53 in tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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