Thermo Fisher Scientific Human CD267 (TACI) Synthetic Peptide
Human TACI(CD267) 단백질의 아미노 말단 15개 아미노산 서열을 기반으로 한 합성 펩타이드. Blocking assay 등 다양한 연구용으로 사용 가능. BAFF와 APRIL 관련 면역 반응 연구에 적합. -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids at the amino terminus of human TACI.
PEP-0097 can be used as a blocking peptide with polyclonal antibody PA5-19972.
Target Information
Members of the TNF superfamily regulate immune responses and induce apoptosis.
Two novel members in the TNF family, BAFF (BLyS/TALL-1/THANK/zTNF4) and APRIL (TALL-2), have been identified.
BAFF acts as a B cell activator, inducing B cell proliferation and immunoglobulin secretion, while APRIL regulates both immunological and non-immunological cell growth.
Three receptors—BCMA, TACI, and BAFF-R—bind BAFF and APRIL.
TACI and its ligands regulate humoral immune responses, activate NF-κB and c-Jun N-terminal kinase, and are involved in B cell-associated autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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