
Thermo Fisher Scientific PDE3B Polyclonal Antibody, Biotin
Biotin으로 표지된 Thermo Fisher Scientific PDE3B 폴리클로날 항체로, WB, IHC, ICC, ELISA 등 다양한 응용 가능. Rabbit IgG 기반으로 여러 종에 반응하며, 지방 대사 및 신호전달 연구에 적합. 고순도 친화 크로마토그래피 정제 제품.
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Thermo Fisher Scientific PDE3B Polyclonal Antibody, Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1050–2000 on mouse PDE3B protein; labels all variants of PDE3B |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cyclic nucleotide phosphodiesterase with dual specificity for second messengers cAMP and cGMP, which are key regulators of many physiological processes. PDE3B may play a role in fat metabolism and regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6, it assembles a signaling complex activating the PI3K gamma complex, contributing to angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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