Thermo Fisher Scientific GDF15 Polyclonal Antibody
Rabbit Polyclonal GDF15 항체로 Western blot에 최적화됨. Human 시료 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA529782
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GDF15 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Recommended positive controls: 293T, A431, HeLa
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–308 of Human GDF-15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2547256 |
Target Information
GDF-15 belongs to the TGF-beta cytokine family, which plays an important role during prenatal development, postnatal growth, and tissue maintenance. GDF-15 is predominantly expressed in the placenta and, to a lesser extent, in other tissues. Its presence in amniotic fluid and elevated serum levels in pregnant women suggest involvement in gestation and embryonic development.
GDF-15 generally exhibits tumor-suppressive activity and is a major factor secreted in response to p53 pathway activation. Serum GDF-15 levels are positively correlated with progression of several cancers, including colorectal, pancreatic, and prostate tumors.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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