Thermo Fisher Scientific GDF15 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000
• Recommended positive controls: 293T, A431, HeLa

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Product Specifications

Target Information

GDF-15 belongs to the TGF-beta cytokine family, which plays an important role during prenatal development, postnatal growth, and tissue maintenance. GDF-15 is predominantly expressed in the placenta and, to a lesser extent, in other tissues. Its presence in amniotic fluid and elevated serum levels in pregnant women suggest involvement in gestation and embryonic development.
GDF-15 generally exhibits tumor-suppressive activity and is a major factor secreted in response to p53 pathway activation. Serum GDF-15 levels are positively correlated with progression of several cancers, including colorectal, pancreatic, and prostate tumors.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.