Thermo Fisher Scientific ABCC11 Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: NSKIILIDEA TASIDMETDT LIQRTIREAF QGCTVLVIAH RVTTVLNCDH
• For short term use, store at 2–8°C up to 1 week.
• For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology: Cow 86%; Dog 86%; Guinea Pig 86%; Horse 93%; Human 100%; Mouse 86%; Rabbit 86%; Rat 86%; Yeast 86%

Target Information

ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This ABC full transporter belongs to the MRP subfamily, which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides.
In addition, a SNP in this gene determines human earwax type. This gene and ABCC12 are derived by duplication and both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.