Thermo Fisher Scientific CD205 Monoclonal Antibody (IL-A114)
소, CD205(DEC205)을 인식하는 IL-A114 클론의 마우스 단클론 항체. IHC(F) 및 유세포분석에 사용 가능. 단백질 G 정제, PBS 버퍼 및 0.09% sodium azide 포함. 연구용으로만 사용.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL-A114 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745281 |
Additional Formats
Product Specific Information
Mouse anti-Bovine CD205 antibody, clone IL-A114 recognizes bovine CD205 (also known as DEC205) and was originally described as BoWC6.
Target Information
CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking, and presentation that enhances antigen-specific T cell immunity.
CD205 is highly expressed by CD8+ dendritic cells (DCs) and variably expressed by bone marrow Gr1+ cells, Langerhans cells, bone marrow-derived DCs (BMDC), and thymic epithelial cells.
It acts as an endocytic receptor that directs captured antigens toward specialized antigen processing regions and can reduce B lymphocyte proliferation.
Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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