Thermo Fisher Scientific Phospho-Phospholamban (Ser16) Polyclonal Antibody
Phospho-Phospholamban (Ser16) 특이적 항체로 심근 세포 내 칼슘 펌프 조절 연구에 적합. Western blot에 최적화된 고순도 Rabbit Polyclonal IgG. 다양한 종에서 반응하며, 항원 친화 크로마토그래피로 정제된 액상 형태.
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Applications
- Western Blot (WB): 0.5–2 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Rabbit |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (KLH-conjugated) corresponding to residues R(14) A [pS] T I E M P Q Q A R(25) C of human cardiac Phospholamban |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.4, with 30% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_795167 |
Product Specific Information
- Recommended positive control: Bovine cardiac preparation
- PA1-25784 is expected to cross-react with rabbit, mouse, rat, canine, and porcine due to sequence homology
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phospholamban (PLB) is a 52 amino acid phosphoprotein that regulates the calcium pump of cardiac sarcoplasmic reticulum (SR).
PLB forms an oligomer of five identical subunits, each with a cytoplasmic and transmembrane domain.
The cytoplasmic domain (residues 1–25) contains phosphorylation sites, is highly basic, and readily cleaved by proteases.
The transmembrane domain (residues 25–52) is hydrophobic, protease-resistant, and stabilizes the pentamer.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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