Thermo Fisher Scientific AURKC Monoclonal Antibody (OTI10A7), TrueMAB
AURKC 단백질을 인식하는 Mouse monoclonal 항체로 Western blot 및 Immunocytochemistry에 적합. Human 시료 반응성. 동결건조 형태로 제공되며 PBS buffer에 8% trehalose 포함. 연구용으로 세포주 내 Aurora C 발현 연구에 활용 가능.
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Applications
- Western Blot (WB): 1:500
- Immunocytochemistry (ICC/IF): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A7 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human AURKC expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins. It plays a key role in organizing microtubules related to centrosome/spindle function during mitosis.
AURKC is overexpressed in several cancer cell lines, suggesting involvement in oncogenic signaling. Studies indicate its association with mitotic structures and roles in critical cell cycle events such as centrosome duplication, chromosome segregation, and cytokinesis.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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