Thermo Fisher Scientific ABCC2 (MRP2) Polyclonal Antibody
ABCC2(MRP2) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 IHC에 사용 가능하며, 인간 시료에 반응. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 900–950 of human ABCC2 conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long-term storage, keep at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: ABCC2.
Target Information
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions.
The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain.
It interacts with various cytoskeletal and cell junctional proteins in different tissues and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, apico-basal polarity, and tumor suppression pathways in non-erythroid cells.
Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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