Thermo Fisher Scientific Cytokeratin 10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human KRT10. Recombinant protein control fragment (Product #RP-88807). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytokeratin 10,uniProtId:P13645-1,ncbiNodeId:9606,antigenRange:326-443,antigenLength:584,antigenImageFileName:PA5-82451_Cytokeratin_10_P13645-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82451_Cytokeratin_10_P13645-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789609

Product Specific Information

Immunogen sequence: EQLAEQNRKD AEAWFNEKSK ELTTEIDNNI EQISSYKSEI TELRRNVQAL EIELQSQLAL KQSLEASLAE TEGRYCVQLS QIQAQISALE EQLQQIRAET ECQNTEYQQL LDIKIRLE

Target Information

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.