Thermo Fisher Scientific Cytokeratin 10 Polyclonal Antibody
Human Cytokeratin 10에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, PBS/glycerol buffer에 보관. 연구용으로 피부 및 상피세포 마커 분석에 활용 가능.
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KRT10. Recombinant protein control fragment (Product #RP-88807). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789609 |
Product Specific Information
Immunogen sequence:
EQLAEQNRKD AEAWFNEKSK ELTTEIDNNI EQISSYKSEI TELRRNVQAL EIELQSQLAL KQSLEASLAE TEGRYCVQLS QIQAQISALE EQLQQIRAET ECQNTEYQQL LDIKIRLE
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). Although not typical markers for endothelial cells, some microvascular endothelial cells also express cytokeratins.
There are at least 20 different cytokeratins ranging from 40–70 kDa with isoelectric points of 5–8.5, identifiable via two-dimensional gel electrophoresis.
Cytokeratins are classified into two types:
- Type I: Acidic polypeptides
- Type II: Basic polypeptides
Each epithelial cell expresses at least one member from both types. Monoclonal antibodies against cytokeratin proteins are useful for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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