Thermo Fisher Scientific Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Monoclonal Antibody (AACT/1452)
인간 SERPINA3 단백질을 표적으로 하는 단클론 항체로, 조직학적 마커(Histiocytoma Marker)로 사용 가능. 파라핀 및 PFA 고정 조직에서 IHC에 적합. 단백질 A/G로 정제된 액상 형태이며, 보존제 무첨가. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AACT/1452 |
| Immunogen | Recombinant human Antichymotrypsin (AACT) protein fragment (around aa 49–187) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SERPINA3 encodes Alpha-1-Antichymotrypsin (Alpha-1-ACT), an early-stage acute-phase plasma protein and serine protease inhibitor that preferentially inactivates chymotrypsin, cathepsin G, and chymase.
Alpha-1-ACT is associated with amyloid plaques in Alzheimer’s disease and aged human and monkey brains. Regulation of serine proteases and their inhibitors is critical in neuromuscular differentiation.
Prostate-specific antigen (PSA), a chymotrypsin-like serine protease, predominantly complexes with Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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