Thermo Fisher Scientific UBASH3A Polyclonal Antibody
Thermo Fisher Scientific의 UBASH3A Polyclonal Antibody는 인간 시료에서 UBASH3A 단백질을 검출하기 위한 염소 유래 다클론 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DSGIRISSVFASP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933378 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_061834.1; NP_001001895.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
TULA (T cell ubiquitin ligand, UBASH3A, ubiquitin associated and SH3 domain containing A), also known as STS-2 or CLIP4, is a 661 amino acid protein that localizes to both the nucleus and cytoplasm and contains one SH3 domain and one UBA domain. It is highly expressed in thymus, bone marrow, spleen, and peripheral blood leukocytes. TULA functions as a homodimer or homo-oligomer that interferes with receptor-type tyrosine kinase degradation and promotes accumulation of activated receptors on the cell surface. It is part of an EGFR- and Cbl-containing complex that interacts with ubiquitinated proteins. The gene encoding TULA, located on human chromosome 21, may be involved in the pathogenesis of type I diabetes. Multiple isoforms are produced due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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