Thermo Fisher Scientific PIM2 Polyclonal Antibody
Human PIM2 단백질을 인식하는 Goat Polyclonal Antibody로 WB 및 IHC(P) 실험에 적합. Unconjugated 형태이며 0.5 mg/mL 농도로 제공. TBS 버퍼(pH 7.3, 0.5% BSA, 0.02% sodium azide) 포함, -20°C에서 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KDREAFEAEYRLGP (aa 23–36) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933380 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
PIM2 is a proto-oncogene that phosphorylates BAD, partially inhibiting its apoptotic function. PIM proteins (PIM-1, PIM-2, and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 and shares similar oncogenic functions. It is abundantly expressed in hematopoietic tissues, spleen, thymus, peripheral blood leukocytes, testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion, and increased levels have been observed in certain cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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