Thermo Fisher Scientific DAP3 Monoclonal Antibody (OTI1B5), TrueMAB
Human DAP3 단백질(aa161-398)에 특이적인 Mouse Monoclonal Antibody로 Western Blot에 적합. Affinity chromatography로 정제된 액상 형태이며, PBS/BSA/glycerol buffer에 보관. -20°C에서 보관하며 Freeze/Thaw를 피해야 함. 연구용 전용 시약.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 161–398 of human DAP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are involved in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with an estimated 75% protein to rRNA ratio, opposite to that of prokaryotic ribosomes. Unlike prokaryotic ribosomes, mitoribosomes lack a 5S rRNA. The DAP3 gene encodes a 28S subunit protein that also participates in apoptotic pathways initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein may bind ATP/GTP and act as a functional partner of mitoribosomal protein S27. Splice variants differing in the 5′ UTR have been identified but encode the same protein. Pseudogenes are located on chromosomes 1q and 2q.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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