Thermo Fisher Scientific MYH7 Recombinant Rabbit Monoclonal Antibody (5Q7V6)
MYH7 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot과 ELISA에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, HEK293 세포에서 발현되었습니다. 고순도 친화 크로마토그래피 정제 및 안정적 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:12,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5Q7V6 |
| Immunogen | A synthetic peptide corresponding to amino acids 1700–1800 of human MYH7/beta-MHC (NP_000248.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.09 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094308 |
Product Specific Information
Immunogen sequence:
KLAEQELIET SERVQLLHSQ NTSLINQKKK MDADLSQLQT EVEEAVQECR NAEEKAKKAI TDAAMMAEEL KKEQDTSAHL ERMKKNMEQT IKDLQHRLDE A
Target Information
Muscle myosin is a hexameric protein composed of 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits.
The MYH7 gene encodes the beta (slow) heavy chain subunit of cardiac myosin, predominantly expressed in normal human ventricle and skeletal muscle rich in slow-twitch type I fibers.
Alterations in MYH7 expression are linked to cardiac contractile velocity changes, thyroid hormone depletion, and hemodynamic overload.
Mutations are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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