Thermo Fisher Scientific TPM2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TPM2 protein for WB and ICC/IF applications. Affinity-purified, unconjugated liquid form at 0.5 mg/mL concentration. Suitable for research use only and predicted to react with multiple species.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
Product Specifications
| Property | Description |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human TPM2 (aa 39–48, 224–233) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2633252 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is affinity-purified from rabbit sera and tested for its functionality in various research applications.
This product is intended for research use only and is non-hazardous and non-infectious.
Predicted to react with Monkey, Rabbit, Sheep, and Dog.
Target Information
TPM2 (tropomyosin 2) is beta-tropomyosin, mainly expressed in slow, type 1 muscle fibers. It binds to actin filaments in muscle and non-muscle cells and plays a central role, along with the troponin complex, in calcium-dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon.
Mutations in TPM2 can cause nemaline myopathy 4, arthrogryposis distal 1A/2B, and cap myopathy 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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