Thermo Fisher Scientific PARN Monoclonal Antibody (OTI2D9), TrueMAB
PARN 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P)에서 사용 가능. Human 시료에 반응하며, Affinity chromatography로 정제된 액상 항체. PBS/BSA/glycerol buffer에 보존되며 -20°C에서 보관.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a 3′-exoribonuclease, similar to the RNase D family of 3′-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating mRNA decay in eukaryotic cells. This protein participates in silencing of maternal mRNAs during oocyte maturation and early embryonic development, and in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Alternative splicing variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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