Thermo Fisher Scientific BRD2 Polyclonal Antibody
BRD2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, ICC/IF, IP 등에 사용 가능. 인간 유래 단백질에 반응하며 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 액상 형태로 제공되며 4°C에서 보관.
- 카탈로그번호
- A302582A
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human bromodomain containing 2 (BRD2, UniProt ID: P25440-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 6.8–7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For ICC, formaldehyde fixation is recommended
- Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
This gene encodes a transcriptional regulator belonging to the BET (bromodomains and extra terminal domain) family of proteins. The protein associates with transcription complexes and acetylated chromatin during mitosis, selectively binding the acetylated lysine-12 residue of histone H4 via two bromodomains. The gene is located in the MHC class II region on chromosome 6p21.3, though it is not directly involved in immune response. It has been implicated in juvenile myoclonic epilepsy. Multiple alternatively spliced variants exist, though some full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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