Thermo Fisher Scientific PKP3 Polyclonal Antibody
PKP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태로 1 mg/mL 농도, TBS 기반 버퍼에 보존. 세포 접합부 및 핵에서 발현되는 Plakophilin-3 검출에 적합.
- 카탈로그번호
- PA5119757
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within C-terminal human Plakophilin 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2913329 |
Product Specific Information
- Positive Control: SKBR-3 cell lysates, SW620, rat tongue tissue, human skin tissue, human breast carcinoma tissue
- Subcellular Location: Cell junction, Nucleus
Target Information
Plakophilin-3 is an Armadillo-like protein found in nuclei and desmosomes of epithelial cells. Its expression is largely restricted to epithelial cell types, showing punctate staining along cell borders typical of desmosomal proteins. Additionally, bright nuclear speckles are observed, indicating dual localization in desmosomal plaques and the nucleus. It may be involved in signal transduction between the plasma membrane and nucleus. The human protein has a predicted molecular mass of approximately 87 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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