Thermo Fisher Scientific Human CXCR6 Synthetic Peptide
Human CXCR6 단백질의 N-말단 15 아미노산 서열에 해당하는 합성 펩타이드. CXCR6 항체의 블로킹 펩타이드로 사용 가능. Human 종에 반응하며, 액상 형태로 제공. PBS 버퍼(pH 7.2, 0.1% BSA) 및 0.02% sodium azide 포함. 연구용으로만 사용 가능, -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids at the amino terminus of human Bonzo.
PEP-0061 can be used as a blocking peptide with polyclonal antibody PA5-19936.
Target Information
CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV.
CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells.
It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186.
The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells, and liver endothelial cells.
Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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