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Thermo Fisher Scientific Cofilin 1 Polyclonal Antibody
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Thermo Fisher Scientific Cofilin 1 Polyclonal Antibody

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Cofilin-1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 적용 가능. Human, Mouse, Rat 반응성. 동결건조 형태로 보관 용이하며, 인산화 및 비인산화 형태 모두 인식. 세포 골격 및 세포 형태 연구에 적합.

카탈로그번호
OSC00050W-100UL
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오전 07:25
Thermo Fisher Scientific OSC00050W-100UL Cofilin 1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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563,100원VAT 포함 619,410원

Thermo Fisher Scientific · Thermo Fisher Scientific Cofilin 1 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution Publications
Western Blot (WB) 1:1,000 -
Immunohistochemistry (Paraffin) (IHC (P)) 1:1,000 -
Miscellaneous PubMed (Misc) - View 1 publication

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Published Species Not Applicable
Host / Isotype Rabbit / Ig
Class Polyclonal
Type Antibody
Immunogen A synthetic peptide from the phospho Y140 & S156 of human Cofilin-1 (Cofilin, non-muscle isoform) conjugated to blue carrier protein was used as the antigen.
Conjugate Unconjugated
Form Lyophilized
Concentration Not Determined
Storage Buffer Whole serum
Contains No preservative
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
  • The peptide is homologous in rat and mouse.
  • Specificity: Cofilin-1. Recognizes both phosphorylated and unphosphorylated forms.

Target Information

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics and is crucial for normal mitosis and cytokinesis. Plays a role in cell morphology and cytoskeletal organization. Required for the regulation of atypical chemokine receptor ACKR2 trafficking, enhancing chemokine uptake and degradation. Essential for neural tube morphogenesis and neural crest cell migration.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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