Thermo Fisher Scientific ATG16L1 Polyclonal Antibody
ATG16L1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 사용 가능하며, 인간과 생쥐 시료에 반응. 합성 펩타이드 항원 기반, 동결건조 형태로 제공. 연구용 전용 제품.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:100–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of human autophagy-related protein 16-1 (ATG16L1, APG16L) conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: ATG16L1.
Target Information
Autophagy related protein 16L is encoded by the ATG16L gene located on chromosome 2 in humans.
Also known as WD30 or IBD10 (Inflammatory Bowel Disease 10).
ATG12 and ATG5 conjugate and oligomerize with ATG16L to form an 800 kDa Atg16L complex, which facilitates lipidation of LC3 to phosphatidylethanolamine (PE).
This conjugation system serves as a key marker for autophagy.
The ATG16L complex, along with ATG18 and ATG21, prevents premature cleavage of ATG8-PE by the cysteine protease Atg4 until autophagosome completion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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