Thermo Fisher Scientific FXYD7 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Peptide sequence: MATPTQTPTK APEEPDPFYY DYNTVQTVGM TLATILFLLG ILIVISKKVK
• Sequence homology: Cow: 77%; Human: 100%

Target Information

The specific function of this protein remains unknown. This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence.
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing seven invariant and six highly conserved amino acids.

The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator.
Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane.
FXYD2, also known as the gamma subunit of the Na, K-ATPase, regulates the properties of that enzyme.
FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems.
This gene product, FXYD7, is novel and has not been characterized as a protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.