Thermo Fisher Scientific KLF7 Polyclonal Antibody
KLF7 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 고순도 Affinity chromatography 정제, PBS/glycerol 저장. 인간 및 마우스 반응성. 연구용으로만 사용.
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Thermo Fisher Scientific KLF7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KLF7 (Accession O75840), corresponding to amino acid residues V178–K228 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850776 |
Product Specific Information
Antibody detects endogenous levels of total KLF7.
Target Information
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members of this family regulate cell proliferation, differentiation, and survival, and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites.
This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes.
A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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