Thermo Fisher Scientific PSMD11 Polyclonal Antibody
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PSMD11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합합니다. 인간 및 마우스 반응성, 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific PSMD11 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PSMD11 (Accession O00231), corresponding to amino acid residues S272–H322 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850780 |
Product Specific Information
Antibody detects endogenous levels of total PSMD11.
Target Information
The 26S proteasome (PSMD11) is a multicatalytic proteinase complex composed of two complexes: a 20S core and a 19S regulator.
- The 20S core comprises four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits).
- The 19S regulator consists of a base (six ATPase subunits and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome plays a crucial role in processing class I MHC peptides.
PSMD11 is a non-ATPase subunit of the 19S regulator.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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