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Thermo Fisher Scientific TIA-1 Polyclonal Antibody
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Thermo Fisher Scientific TIA-1 Polyclonal Antibody

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Rabbit polyclonal antibody recognizing human TIA-1. Suitable for WB, IHC(P), and ICC/IF. Supplied as a liquid, unconjugated form at 0.65 mg/mL. Recommended storage at -20°C. For research use only.

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Thermo Fisher Scientific PA592843 TIA-1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific TIA-1 Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution
Western Blot (WB) 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:50–1:200
Immunocytochemistry (ICC/IF) 1:20–1:100

Product Specifications

Specification Description
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1–193 of human TIA1
Conjugate Unconjugated
Form Liquid
Concentration 0.65 mg/mL
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Wet ice
RRID AB_2806511

Product Specific Information

Immunogen sequence:
MEDEMPKTLY VGNLSRDVTE ALILQLFSQI GPCKNCKMIM DTAGNDPYCF VEFHEHRHAA AALAAMNGRK IMGKEVKVNW ATTPSSQKKD TSSSTVVSTQ RSQDHFHVFV GDLSPEITTE DIKAAFAPFG RISDARVVKD MATGKSKGYG FVSFFNKWDA ENAIQQMGGQ WLGGRQIRTN WATRKPPAPK STY

Positive Samples: BT-474
Cellular Location: Cytoplasmic granule, Nucleus

Target Information

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from:

  1. A WNT protein (WNT3A) to stabilize beta-catenin
  2. Noggin, a bone morphogenetic protein inhibitor

Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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