Thermo Fisher Scientific CAF1 p60 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 270-559 of human p60 CAF1 (NP_0054321) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CAF1 p60,uniProtId:Q13112-1,ncbiNodeId:9606,antigenRange:270-559,antigenLength:559,antigenImageFileName:PA5-92855_CAF1_p60_Q13112-1_Rabbit.svg,antigenImageFileNamePDP:PA5-92855_CAF1_p60_Q13112-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.64 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806517

Product Specific Information

Immunogen sequence: SRKNLKRPIA HLPCPGKATL AVRCCPVYFE LRPVVETGVE LMSLPYRLVF AVASEDSVLL YDTQQSFPFG YVSNIHYHTL SDISWSSDGA FLAISSTDGY CSFVTFEKDE LGIPLKEKPV LNMRTPDTAK KTKSQTHRGS SPGPRPVEGT PASRTQDPSS PGTTPPQARQ APAPTVIRDP PSITPAVKSP LPGPSEEKTL QPSSQNTKAH PSRRVTLNTL QAWSKTTPRR INLTPLKTDT PPSSVPTSVI STPSTEEIQS ETPGDAQGSP PELKRPRLDE NKGGTESLDP; Positive Samples: HeLa, 293T, MCF7, U-251MG; Cellular Location: Cytoplasm, Nucleus

Target Information

Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF-1 are conserved among human, yeast, and Drosophila.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.