Thermo Fisher Scientific LRFN5 Polyclonal Antibody
LRFN5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간, 마우스, 랫트 반응성. 장기 보관 시 -20°C에서 안정적이며 신경계 연구용으로 적합.
- 카탈로그번호
- OSL00016W-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from cytoplasmic domain of mouse LRFN5 (SALM5) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in human and rat.
- Specificity: LRFN5.
Target Information
LRFN5 is one of a family of five transmembrane glycoproteins highly expressed in neuronal tissues.
LRFN proteins share a leucine-rich repeat (LRR), immunoglobulin-like (Ig), and fibronectin type III (Fn) domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family.
Expression of LRFN1, -3, and -4 mRNA is detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression is primarily restricted to mature cells.
LRFN1, -2, and -4 bind to PDZ domains of postsynaptic PSD95, redistributing PSD95 to the cell periphery.
It is suggested that Lrfn proteins play roles in developing and/or mature vertebrate nervous systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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