Thermo Fisher Scientific HKDC1 Polyclonal Antibody
HKDC1 단백질을 인식하는 Thermo Fisher의 토끼 폴리클로날 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며 인간, 생쥐, 랫드에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C 또는 -20°C에서 보관합니다. 연구용으로만 사용됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HKDC1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 58–341 of HKDC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.45 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| RRID | AB_2553204 |
Product Specific Information
- Recommended positive control: 293T
- Predicted reactivity: Mouse (92%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The epidermal growth factor receptor (HKDC1; ErbB-1; HER1 in humans) is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. It belongs to the ErbB family of receptor tyrosine kinases, which includes HKDC1 (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3), and Her 4 (ErbB-4).
HKDC1 is activated by binding specific ligands such as epidermal growth factor and transforming growth factor alpha (TGFα). These molecules are involved in cell proliferation, differentiation, motility, survival, and tissue development.
Overexpression or overactivity of HKDC1 has been associated with several cancers, including lung cancer and glioblastoma multiforme. A specific mutation, HKDC1vIII, is often observed in glioblastoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.