Thermo Fisher Scientific HOXA5 Polyclonal Antibody
Rabbit polyclonal antibody against HOXA5 for Western blot applications. Recognizes human HOXA5, with predicted reactivity to mouse, pig, and bovine. Supplied as liquid form, 1 mg/mL, purified by antigen affinity chromatography. Suitable for research us...
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Applications
- Western Blot (WB): 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–203 of HOXA5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| RRID | AB_2553207 |
Product Specific Information
- Recommended positive control: human HOXA5-transfected 293T.
- Predicted reactivity: Mouse (96%), Pig (96%), Bovine (97%).
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.
The HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation.
Methylation of this gene may lead to loss of expression. Since the encoded protein upregulates the tumor suppressor p53, HOXA5 may play an important role in tumorigenesis.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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