Thermo Fisher Scientific CRIPTO Monoclonal Antibody (1F10)
인간 CRIPTO(TDGF1) 단백질을 인식하는 마우스 모노클로날 항체. Western blot 및 IHC(Paraffin) 실험에 적합. Protein G 정제된 액상 형태로 제공되며, 장기 보관을 위해 -20°C에서 저장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F10 |
| Immunogen | KLH conjugated synthetic peptide derived from human CRIPTO / Teratocarcinoma-derived growth factor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cripto (TDGF1) is a GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during early embryo development, and in adults it is reactivated in a wide range of epithelial cancers.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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