Thermo Fisher Scientific NR5A1 Monoclonal Antibody (OTI1F2), TrueMAB
Human NR5A1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합. 동결건조 형태로 제공되며 PBS 버퍼에 8% 트레할로스 포함. -20°C 보관, 반복 동결/해동 피해야 함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–262 of human NR5A1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland.
SF-1 regulates transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family and contains two activation function domains (AF1 and AF2) necessary for interactions with other nuclear receptors and coactivators such as SRC-1, GRIP1, CBP, and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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