Thermo Fisher Scientific NR5A1 Monoclonal Antibody (OTI10E2), TrueMAB
Human NR5A1 단백질(아미노산 1-262)에 특이적인 마우스 단클론 항체. 면역조직화학(IHC) 검증 완료. 무보존제, 동결건조 형태로 제공. 내분비계 발달 연구 및 스테로이드 생성 관련 단백질 분석에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10E2 |
| Immunogen | Human recombinant protein fragment (aa 1–262 of NR5A1) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland.
SF-1 promotes transcriptional activity of steroidogenic enzymes from the cytochrome P450 family and contains two activation function domains (AF1 and AF2) necessary for interaction with other nuclear receptors, coactivators, and corepressors such as SRC-1, GRIP1, CREB-binding protein (CBP), and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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